perimenopause

Frozen Shoulder: Unravelling the Complexities and Providing Clarity

Written by Michael Crawley, BSc, BPT, CSCS

Nearly 100 years ago, Earnest Codman coined the term “frozen shoulder” and highlighted three clinical issues (Salamh et al. 2025):

  • Difficult to define

  • Difficult to treat

  • Difficult pathology to explain to patients

Those three points still hold true today.

Multiple structures and pathological findings have been implicated in the development of frozen shoulder. This includes the accumulation of immune system mediators, thickening of ligaments, and altered collagen translation (Pandey and Madi 2021). Clinically, this presents as a shoulder with reduced range of motion in both active and passive flexion, abduction, and external rotation (as seen in the image below).

Figure 1: Reduced Shoulder range of motion (ROM) with frozen shoulder

The Real Impact of Frozen Shoulder

A scoping review examining how people experience and live with frozen shoulder demonstrates how debilitating and impactful the condition can be. King and Hebron (2023) identified five major themes:

  1. “Dropping me to my knees, due to the pain”

  2. Struggle for normality

  3. Emotional change for self

  4. Challenges through the healthcare journey

  5. Coping & adapting

This highlights that frozen shoulder is not just a physical limitation. It can significantly alter how someone functions and experiences their daily life.

Unfortunately, frozen shoulder demonstrates a bias towards a particular demographic. Females in the 40–60 age category take the brunt of diagnoses. To rub salt in the wounds, females are more likely to experience a more prolonged and symptomatic course compared to male counterparts.

Types of Frozen Shoulder

Frozen shoulder can be broadly classified into two categories (Pandey and Madi 2021):

Primary:
A stiff shoulder developing with no known cause. However, there are commonly linked conditions, most notably diabetes mellitus and thyroid dysfunction. The incidence of frozen shoulder can reach as high as 30% in individuals with diabetes.

Secondary:
A stiff shoulder with an underlying cause such as direct trauma (e.g. a fall), infection, or inflammatory conditions.

The Three Stages of Frozen Shoulder

Frozen shoulder follows a series of stages, delineated by changing symptoms (Date and Rahman 2020). While approximate timelines are often attached, there is significant variability, and for some individuals, full resolution may not occur within 3–5 years.

Freezing Stage (Stage 1: 2–6 months)

  • Predominantly characterised by moderate to severe pain and partial restriction of ROM

  • Early stages may present with pain and only terminal loss of ROM

This stage can be confused with rotator cuff tendinopathy. However, ROM does not progressively worsen in tendinopathy, whereas it continues to worsen with each follow-up in frozen shoulder.

Frozen Stage (Stage 2: 4–12 months)

  • Characterised by both pain and stiffness in varying proportions

  • Early phase tends to be more pain-dominant

  • Later phase becomes more stiffness-dominant

Thawing Stage (Stage 3: 6–26 months)

  • Characterised by minimal pain

  • Gradual resolution of stiffness

  • Progressive return of movement

Pathologically, this reflects a gradual reduction in inflammation and restoration of movement.

Treatment and Management Across the Stages

What actually works, and when it matters

The research on the effectiveness of treatments for frozen shoulder remains conflicting. However, a conservative approach is typically recommended as the starting point (Date and Rahman 2020).

Common interventions include:

  • Analgesics

  • Physiotherapy

  • Intra-articular injections

  • Suprascapular nerve block

Early Stage: Movement Within Tolerance

In the early stage of frozen shoulder, gentle stretching and mobility exercises within a pain-free range are advised (Date and Rahman 2020).

Creativity can play a key role here, as Louis Gifford, the brilliant pain specialist, stresses. In his book Aches and Pains, he explains how adjusting body position can influence the amount of pain-free range available to a limb.

The videos below demonstrates this concept. The key idea is simple:

  • The arm can move relative to the body

  • Or the arm can stay fixed while the body moves around it

Shoulder Range of Motion Wall Drills:
https://youtu.be/9_GwO7r24hM

Passive and active-assisted exercises can also be incorporated. These reduce the working stress on affected structures, allowing the humerus to move through range without generating or exacerbating pain.

Active Assisted and Passive Shoulder:
https://youtu.be/072jZDVW-ac

As Pain Settles: Introducing Strength

As pain begins to reduce and become more manageable, strengthening exercises can be introduced.

Here, the principle that “the dose and position make the poison” becomes particularly relevant.

Using isometrics in varying positions and directions allows for global loading through the shoulder while staying within tolerable limits.

Entry Level Isometric:
https://youtu.be/mDzgyyKlzZo

Later Stages: What Are Mobilisations Actually Doing?

Mobilisations performed by a physiotherapist in the later stages have shown some utility. However, the mechanism behind their effectiveness is contested.

For many years, the prevailing thought was that inferior mobilisation directly impacted the shoulder joint capsule. However, Jeremy Lewis, a well-known Australian shoulder specialist, has pointed out that a physiotherapist would need to generate approximately 600kg of force to meaningfully affect the capsule.

I am not aware of many Canadians with a 600kg deadlift.

The best approach at this stage would be to continue to progress strength training through pain free range.

Injections and Medical Management: Timing Is Key

Outside of physiotherapy, injections and pharmacological treatments are often used.

Nonsteroidal anti-inflammatories have shown little impact in the case of frozen shoulder. Intra-articular steroid injections, however, have demonstrated positive effects, particularly when used at the right time.

Again, Jeremy Lewis stresses that these injections must be used in the early stages, when pain is highest. This reinforces the importance of early and accurate diagnosis.

A similar pattern is seen with suprascapular nerve blocks, which can also have a positive effect on pain relief when applied early (Date and Rahman 2020).

Surgical Options: Often Less Helpful Than Expected

Surgical options are available, but often yield little additional benefit.

Beard et al. (2018) found no clinically significant benefit of shoulder arthroscopy compared to sham surgery. This was further supported by the large UK FROST trial (Corbacho et al. 2021), which reported that early physiotherapy was more cost-effective and accessible compared to invasive and costly surgical approaches.

Interestingly, manipulation under anaesthetic, which previously had negative connotations, has shown some efficacy. This likely relates to the reduction of muscle guarding and tension that can develop with frozen shoulder. When under anaesthetic, this guarding effect is temporarily removed.

Looking Beyond the Shoulder

An important point that is often not expressed or evaluated in the research is that frozen shoulder may be a sign of broader health issues, stemming from multiple systems in the body.

In many cases, it can act as a wake-up call to incorporate strength and conditioning into your lifestyle and address other health metrics.

You may not be able to train the affected side in the same way, but there are still many full-body exercises that can be performed without exacerbating the shoulder:

  • Towing a sled

  • Belt squat

  • Walking lunges

  • Step-ups

Why This Matters

There are three key reasons why this approach is important:

  1. Approximately 1 in 5 people go on to develop similar symptoms in the opposite shoulder (Pandey and Madi 2021)

  2. Sedentary individuals are more likely to receive a frozen shoulder diagnosis

  3. Well-designed strength and conditioning programs can positively influence the systems linked to frozen shoulder development, including endocrine, immune, and cardiovascular systems

Deeper Dive into Causation and Management

Recent research has continued to highlight the multi-faceted nature of frozen shoulder and the challenges associated with its management (Navarro-Ledesma 2025a).

This is not a condition driven by a single structure or isolated tissue. Instead, it reflects the interaction of multiple systems within the body.

The diagram below highlights this well. Rather than being caused by one specific issue, frozen shoulder appears to sit at the intersection of several physiological systems, all of which can influence one another.

Estrogen and Menopause

One of the more consistent patterns seen in the research is the increased prevalence of frozen shoulder in peri-menopausal women. This has led to estrogen being identified as a key player in its development (Wend et al. 2012).

As shown in figure below, estrogen has effects that extend well beyond the reproductive system. Its influence spans multiple systems that are directly relevant to frozen shoulder.

Neuroendocrine System

Declining estrogen levels can influence the nervous system through several mechanisms, impacting pain thresholds, resilience to stress, and central sensitisation.

A useful way to think about this is the “fire alarm” analogy.

You leave the bacon on the grill too long and the fire alarm goes off because of the smoke. There is no fire, but the system reacts as if there is.

With reduced estrogen levels, the threshold for triggering that “alarm” can become lower. The result is an amplified pain experience, even when the underlying tissue irritation may not fully justify it.

Metabolic System

Estrogen also plays a key role in fat metabolism, glucose regulation, and resistance to oxidative stress.

When these systems are disrupted, it can create an internal environment where tissue repair is compromised. This contributes to fibrosis, which is a hallmark of frozen shoulder.

Immune System

The same pattern continues within the immune system.

Declining estrogen levels tend to promote a more pro-inflammatory state. Immune system mediators accumulate within the tissues involved in frozen shoulder, and when combined with metabolic dysfunction, this can further drive the condition.

Targeting the System, Not Just the Shoulder

The research highlights how frozen shoulder is influenced by multiple systems, not just the shoulder itself. As a result, management is not limited to physiotherapy or surgical intervention alone.

There are a number of factors that could be explored here, but for the purpose of this piece, three of the more relevant and actionable areas will be discussed below.

Strength and Conditioning

Well-designed and properly implemented strength and conditioning programs have demonstrated positive impacts on estrogen levels, muscle mass, and fat mass in menopausal women (Razzak et al. 2019).

As mentioned previously, even with an impacted and painful shoulder, this does not mean avoiding training altogether or waiting for full resolution before doing anything.

The whole-body and multi-system benefits of strength training can influence long-term outcomes indirectly. While the shoulder itself may be limited, the broader physiological adaptations still matter.

Nutrition

Diet quality also plays a meaningful role.

A nutritional approach centred around higher-quality, minimally processed foods has been shown to impact symptom severity in individuals with frozen shoulder (Hamed-Hamed et al. 2026).

In practice, the decision to implement a structured strength training program often leads to improvements in other lifestyle behaviours, including dietary choices.

In the same way that hormonal, metabolic, and immune factors can drive the development of frozen shoulder, lifestyle decisions can push back against these drivers. This not only has the potential to improve current symptoms, but also to reduce the likelihood of future development.

Sleep and Circadian Rhythm

Circadian rhythm and sleep regulate inflammatory processes, hormonal release, and tissue repair (Navarro-Ledesma 2025a).

These are central to both general health and the development and recovery of frozen shoulder, as well as adaptation to strength training and exercise.

This is where the entanglement of systems becomes more apparent.

Bringing It Together

Sleep, exercise, and nutrition can be thought of as a three-legged stool. Each supports the others, and removing one weakens the entire system.

Addressing these factors will not provide an immediate solution to frozen shoulder. However, they can set the conditions for recovery and reduce the likelihood of recurrence, particularly when considering that approximately 20% of individuals will experience similar symptoms in the opposite shoulder.

Summary and Takeaways

Frozen shoulder is a systems issue, not just a joint problem

Frozen shoulder is not a local condition. It can have significant and long-term effects on both physical and psychological well-being.

In some cases, it can be so debilitating that it alters how an individual functions day to day. That may sound hyperbolic, but when revisiting the five themes outlined earlier, alongside the number of systems involved, it becomes more understandable.

Approaching treatment with a reductionist lens, relying solely on an injection or a home exercise program, is akin to using a hammer where a scalpel is required. This sentiment is supported in a recent review by Brindisino et al. (2026).

Effective management requires a more nuanced and personalised approach that considers the multiple drivers involved:

  • Hormonal (endocrine)

  • Immune system (autoimmune / inflammatory)

  • Strength, mobility, and capacity

  • Cardiovascular health

  • Pain psychology (sensitisation and emotional drivers)

  • Structural factors

  • Circadian rhythm and sleep

Key Takeaways

  • General strength training can still be completed and is beneficial with a frozen shoulder diagnosis

  • Surgical interventions are often unwarranted and do not demonstrate superior outcomes

  • Frozen shoulder is multi-factorial, and lifestyle factors such as exercise, nutrition, and sleep play a critical role in both management and risk reduction

References

Beard, D. J. et al. 2018. Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial. The Lancet 391(10118), pp. 329-338. doi: 10.1016/S0140-6736(17)32457-1

Brindisino, F. et al. 2026. Beyond the capsule: an integrated perspective on the wide world of frozen shoulder. A collaborative viewpoint. Pain Management, pp. 1-20. doi: 10.1080/17581869.2026.2636725

Corbacho, B. et al. 2021. Cost-effectiveness of surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder : an economic evaluation of the UK FROST trial. Bone Jt Open 2(8), pp. 685-695. doi: 10.1302/2633-1462.28.Bjo-2021-0075.R1

Date, A. and Rahman, L. 2020. Frozen shoulder: overview of clinical presentation and review of the current evidence base for management strategies. Future Sci OA 6(10), p. Fso647. doi: 10.2144/fsoa-2020-0145

Hamed-Hamed, D. et al. 2026. Impact of nutritional profile on pain and functionality in patients with frozen shoulder: a cross-sectional observational study. Frontiers in Medicine Volume 13 - 2026,  doi: 10.3389/fmed.2026.1785577

King, W. V. and Hebron, C. 2023. Frozen shoulder: living with uncertainty and being in “no-man’s land”. Physiotherapy Theory and Practice 39(5), pp. 979-993. doi: 10.1080/09593985.2022.2032512

Navarro-Ledesma, S. 2025a. Frozen Shoulder as a Systemic Immunometabolic Disorder: The Roles of Estrogen, Thyroid Dysfunction, Endothelial Health, Lifestyle, and Clinical Implications. J Clin Med 14(20),  doi: 10.3390/jcm14207315

Navarro-Ledesma, S. 2025b. Frozen Shoulder as a Systemic Immunometabolic Disorder: The Roles of Estrogen, Thyroid Dysfunction, Endothelial Health, Lifestyle, and Clinical Implications. Journal of Clinical Medicine 14(20), p. 7315. 

Pandey, V. and Madi, S. 2021. Clinical Guidelines in the Management of Frozen Shoulder: An Update! Indian J Orthop 55(2), pp. 299-309. doi: 10.1007/s43465-021-00351-3

Razzak, Z. A. et al. 2019. Effect of aerobic and anaerobic exercise on estrogen level, fat mass, and muscle mass among postmenopausal osteoporotic females. Int J Health Sci (Qassim) 13(4), pp. 10-16. 

Salamh, P. et al. 2025. An international consensus on the etiology, risk factors, diagnosis and Management for individuals with Frozen Shoulder: a Delphi study. J Man Manip Ther 33(4), pp. 309-320. doi: 10.1080/10669817.2025.2470461


Wend, K. et al. 2012. Tissue-Specific Effects of Loss of Estrogen during Menopause and Aging. Frontiers in Endocrinology Volume 3 - 2012,  doi: 10.3389/fendo.2012.00019

Osteopenia and Strength Training for Women: What Happens Before Menopause

Written by Evelyn Calado, MKin, CSCS, RKin

There is a persistent misconception that bone loss is something that “just happens” after menopause. By the time many women start thinking seriously about bone density, the process of loss is already well underway.

Osteopenia and strength training are directly linked, yet most women are not told how early bone loss actually begins.

Bone health is not a passive outcome of aging. It is an active, dynamic process shaped by hormones, mechanical loading, and energy availability across the entire female lifespan.

Understanding osteopenia requires understanding one central principle: bone is living tissue, constantly undergoing remodeling through the opposing actions of osteoblasts and osteoclasts.

Bone Remodeling: The Balance Between Formation and Breakdown

At any given moment, your skeleton is not static. It is metabolically active.

  • Osteoblasts are responsible for bone formation

  • Osteoclasts are responsible for bone resorption

In a healthy system, these processes are tightly coupled. Bone that is broken down is replaced with new, strong bone. The integrity of your skeleton depends on the balance between these two forces.

Estrogen plays a critical regulatory role in maintaining this equilibrium.

Estrogen as a Regulator of Bone Turnover

Estrogen is not just a reproductive hormone. It is deeply involved in musculoskeletal health.

It functions, in part, by:

  • Inhibiting excessive osteoclast activity

  • Supporting osteoblast survival and activity

When estrogen levels are stable, bone turnover remains balanced. But when estrogen becomes low or erratic, this regulatory system begins to fail.

Estrogen does not “leach calcium from bone.” Its decline removes inhibitory control over osteoclasts, allowing bone resorption to outpace formation.

The result is a gradual reduction in bone mineral density, what we clinically recognize as osteopenia, and eventually osteoporosis if left unchecked.

Perimenopause: The Underappreciated Inflection Point

Much of the conversation around bone health focuses on postmenopause. However, perimenopause is a critical and often overlooked phase.

This is not simply a state of low estrogen. It is a state of hormonal volatility.

During perimenopause:

  • Estrogen levels fluctuate unpredictably

  • Progesterone exposure becomes inconsistent

  • The coordination of tissue remodeling processes becomes impaired

These fluctuations influence:

  • Bone turnover

  • Muscle protein synthesis

  • Recovery capacity

The net effect is a physiological environment that becomes increasingly catabolic, meaning tissue breakdown can begin to exceed tissue formation.

This is why bone density decline can begin before menopause is complete.

The Muscle–Bone Unit: Why Strength Matters

Bone does not exist in isolation. It is functionally linked to muscle through what is often referred to as the muscle–bone unit.

When muscle contracts, it exerts mechanical force on bone. This mechanical strain is the primary stimulus for bone adaptation.

Without sufficient loading, the body interprets bone as metabolically expensive and unnecessary, and osteoclastic activity increases accordingly.

Strength training directly targets this system.

Through high-load resistance exercise:

  • Muscle force increases

  • Mechanical strain on bone increases

  • Osteoblast activity is stimulated

  • Bone mineral density is preserved or improved

This is not a marginal effect. It is one of the most powerful non-pharmacological interventions available for maintaining skeletal integrity.

If you are unsure where to start, this is exactly where an individualized approach matters. [Start with an Initial Assessment]

Why Endurance Alone Is Not Enough

Many active women assume that being “fit” is sufficient to protect bone health. However, endurance training does not provide the same osteogenic stimulus as resistance training.

In fact, without adequate nutrition and strength work, high volumes of endurance exercise can:

  • Increase cortisol and systemic stress

  • Contribute to low energy availability

  • Impair bone formation

Bone health requires specific, targeted mechanical loading, not just general activity.

Why Strength Training Is Essential for Women’s Bone Health

Dr. Stacy Sims is explicit. Strength training is not optional for women. It is a lifelong requirement.

General recommendations include:

  • At least 2 to 3 strength sessions per week

  • Emphasis on heavy resistance, not just light weights

  • Inclusion of compound lifts and power-based movements

This becomes even more critical during perimenopause and beyond, when:

  • Muscle mass becomes harder to maintain

  • Hormonal support for tissue repair declines

  • The risk of accelerated bone loss increases

Strength training is not simply about preserving aesthetics or performance. It is about maintaining structural integrity.

For most people, this requires structure, progression, and accountability. [Explore Personal Training Options]

The Compounding Effect of Muscle Loss

Muscle loss and bone loss are interconnected.

As muscle mass declines:

  • Mechanical loading on bone decreases

  • Bone formation signals weaken

  • Risk of fragility increases

Hormonal environments during this phase can also increase muscle protein breakdown, making it harder to maintain lean mass without intentional intervention.

This creates a feedback loop:

Less muscle leads to less bone stimulus, which leads to weaker bone and higher injury risk.

Strength training interrupts this cycle.

Bone Health Is Built, Not Preserved

One of the most important reframes is this:

You are not trying to hold on to bone. You are trying to continually build and reinforce it.

Bone is responsive tissue. It adapts to the signals it receives.

  • If the signal is inactivity, bone loss occurs

  • If the signal is chronic stress without adequate fuel, bone loss occurs

  • If the signal is heavy loading with adequate nutrition, bone strength improves

Perimenopause does not mark the end of this adaptability. It simply raises the stakes.

Final Thoughts

Osteopenia is not an inevitable consequence of aging. It is, in large part, the result of mismatched physiology, where hormonal changes are not met with appropriate mechanical and nutritional support.

Estrogen may set the stage, but behavior determines the outcome.

Strength training, done consistently and with sufficient intensity, provides the necessary stimulus to:

  • Maintain bone mineral density

  • Preserve lean muscle mass

  • Counteract the catabolic shifts of hormonal fluctuation

For women entering perimenopause, this is not optional. It is essential.

And the earlier this foundation is built, the more resilient the system becomes over time.

This is why most of the women we work with are already incorporating structured resistance training before these changes begin. [Learn More About Hybrid Coaching]

Source

Dr. Stacy Sims, ROAR